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胃抽吸物样本中药物的气相色谱鉴定:一种用于急诊毒理学的快速筛查程序。

Gas-chromatographic identification of drugs in gastric aspirate samples: a rapid screening procedure for emergency toxicology.

作者信息

Abramson F P

出版信息

Clin Chem. 1976 Nov;22(11):1906-9.

PMID:975553
Abstract

Gastric aspirate has not been used frequently in the identification of ingested drugs. Because there is only qualitative significance in such a sample, a new method is described that facilitates identification. A 1-ml gastric aspirate sample is extracted with 100 mul of chloroform and analyzed directly by gas chromatography. Seventeen drugs commonly involved in overdose cases are included in this 25-min procedure. The gastric drug screen has been applied to more than 500 patients, and results are described.

摘要

胃抽吸物在确定摄入药物方面并未被频繁使用。由于此类样本仅具有定性意义,因此本文描述了一种有助于鉴定的新方法。取1毫升胃抽吸物样本,用100微升氯仿萃取,然后直接通过气相色谱法进行分析。在这个25分钟的过程中涵盖了17种常见于过量用药病例的药物。胃内药物筛查已应用于500多名患者,并对结果进行了描述。

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