Kaiser S, Jorulf H, Hirsch G
Department of Pediatric Radiology, Astrid Lindgren Children's Hospital, Karolinska Hospital, Stockholm, Sweden.
Acta Radiol. 1998 Sep;39(5):523-31. doi: 10.1080/02841859809172219.
The traditional approach to investigating suspected osteomyelitis in children includes conventional radiography and bone scintigraphy. The roles of US, CT and MR imaging are controversial. Our objective was to determine whether the additional use of these modalities would yield information likely to lead to treatment modification.
Sixty-five children with clinically suspected osteomyelitis took part in a prospective study. All patients underwent conventional radiography and bone scintigraphy. In addition to this, US, CT and MR imaging were all performed in 33 patients; the remaining 32 patients were examined with various combinations of these three modalities. The value of the additional information obtained was estimated retrospectively by a pediatric orthopedic surgeon in terms of possible modification of treatment.
MR imaging was the modality with the highest sensitivity and specificity for detecting osteomyelitis. MR yielded information likely to influence treatment in the greatest proportion of patients (45%) followed by US (30%).
The standard investigation protocol with the addition of US (because of its ability to detect subperiosteal abscesses early and simply) is adequate in uncomplicated cases. When additional imaging is required to outline a lesion, or in complicated cases, and when bone scintigraphy is inconclusive, MR imaging should also be performed. CT should be considered when MR investigation is not available or when anesthesia is required but cannot be provided.
传统的儿童疑似骨髓炎检查方法包括传统X线摄影和骨闪烁显像。超声、CT和磁共振成像(MRI)的作用存在争议。我们的目的是确定额外使用这些检查手段是否能提供可能导致治疗方案改变的信息。
65例临床疑似骨髓炎的儿童参与了一项前瞻性研究。所有患者均接受了传统X线摄影和骨闪烁显像。除此之外,33例患者还进行了超声、CT和MRI检查;其余32例患者接受了这三种检查手段的不同组合检查。一名小儿骨科医生通过回顾性分析评估了所获得的额外信息对治疗方案可能产生的影响。
MRI是检测骨髓炎敏感性和特异性最高的检查手段。MRI对最大比例的患者(45%)提供了可能影响治疗的信息,其次是超声(30%)。
在无并发症的病例中,标准检查方案加上超声(因其能早期且简单地检测骨膜下脓肿)就足够了。当需要额外的影像学检查来明确病变,或在复杂病例中,以及骨闪烁显像结果不明确时,也应进行MRI检查。当无法进行MRI检查或需要麻醉但无法实施时,应考虑使用CT。