Shah S S, Kapadia M S, Meisler D M, Wilson S E
Eye Institute and Department of Cell Biology, The Cleveland Clinic Foundation, Ohio, USA.
Cornea. 1998 Sep;17(5):508-16. doi: 10.1097/00003226-199809000-00008.
The purpose of this study was to evaluate the results of myopic photorefractive keratectomy (PRK) with or without astigmatic keratotomy (AK) for different levels of intended correction by using the SVS Apex laser.
This is a retrospective cohort study of 226 eyes that had PRK for myopia ranging from -1.0 to -7.6 diopters and 6 months of follow-up. In addition, 64 of these eyes had AK for naturally occurring or laser-induced astigmatism. Uncorrected visual acuity, spectacle-corrected visual acuity, and corneal topography with quantitative descriptors of surface regularity (SRI) and surface asymmetry (SAI) were used to monitor the results of PRK with or without AK.
At 6 months, 95.6% eyes had an uncorrected visual acuity of 20/40 or better, 90% eyes were within +/-1.0 diopter of emmetropia, and 3.1% eyes lost two lines of best-corrected vision. No eyes lost more than two lines of best-corrected vision. Mean refractive astigmatism was reduced, but mean SAI and SRI were increased, 6 months after PRK. Uncorrected vision, best-corrected vision, and predictability decreased, whereas SAI and SRI increased, with increasing attempted correction.
PRK, with or without AK, effectively reduced myopia in all eyes by 6 months after surgery. Predictability tended to decrease with increasing attempted correction, even for eyes with relatively low to moderate myopia. PRK may induce surface asymmetry and irregularity at 6 months, and these alterations tend to be greater as the attempted correction increases.
