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家兔臂旁核复合体化学刺激的呼吸反应

Respiratory responses to chemical stimulation of the parabrachial nuclear complex in the rabbit.

作者信息

Mutolo D, Bongianni F, Carfì M, Pantaleo T

机构信息

Dipartimento di Scienze Fisiologiche, Università degli Studi di Firenze, Viale G.B. Morgagni 63, I-50134, Florence, Italy.

出版信息

Brain Res. 1998 Oct 5;807(1-2):182-6. doi: 10.1016/s0006-8993(98)00775-6.

DOI:10.1016/s0006-8993(98)00775-6
PMID:9757031
Abstract

The respiratory role of the parabrachial nuclear complex (PNC) was investigated in alpha-chloralose-urethane anesthetized, vagotomized, paralysed and artificially ventilated rabbits by means of unilateral microinjections (10-20 nl) of 20 mM dl-homocysteic acid. Chemical stimulation elicited three main types of site-specific respiratory effects: excitatory, apneustic and inhibitory responses. The results suggest that the PNC plays a complex role in the control of breathing.

摘要

通过向α-氯醛糖-乌拉坦麻醉、迷走神经切断、麻痹并人工通气的兔单侧微量注射(10 - 20 nl)20 mM的dl-高半胱氨酸,研究了臂旁核复合体(PNC)的呼吸作用。化学刺激引发了三种主要的位点特异性呼吸效应:兴奋、长吸和抑制反应。结果表明,PNC在呼吸控制中发挥着复杂的作用。

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