Fukushima H, Yamaguchi T, Arai T, Nakagawa S, Tsuchiya K, Torii N, Shirai M
Department of Neurosurgery, Tokyo Metropolitan Matsuzawa Hospital, Japan.
No To Shinkei. 1998 Aug;50(8):755-60.
We report a case of glioblastoma manifesting 49 years after a lobotomy. He was diagnosed as having schizophrenia at age 20 and was operated on with a standard lobotomy when he was 27 years old. He had led a useful life after 40 years old without medication. Because of hallucination and delusion, he was hospitalized at the end of 1996. CT showed a well enhanced tumor adjacent to the cavity made by the lobotomy in the left frontal lobe. This is the second case report of glioblastoma just beside the cavity formed by lobotomy. The relationship between glioblastoma and old lobotomy is discussed, especially in regard to morphology and CT findings.
我们报告一例在脑叶切除术后49年出现的胶质母细胞瘤病例。他在20岁时被诊断为精神分裂症，27岁时接受了标准的脑叶切除术。40岁以后他在未服药的情况下过着正常生活。1996年底，由于幻觉和妄想，他住院治疗。CT显示左额叶脑叶切除术后形成的腔隙附近有一个强化明显的肿瘤。这是第二例关于胶质母细胞瘤紧邻脑叶切除术后形成的腔隙的病例报告。本文讨论了胶质母细胞瘤与陈旧性脑叶切除术之间的关系，尤其是在形态学和CT表现方面。
