Kubiczkowa J
Kliniki Otolaryngologicznej Wojskowego Instytutu Medycyny Lotniczej w Warszawie.
Otolaryngol Pol. 1997;51 Suppl 25:230-9.
The authors present a pilot investigation of the effect of betahistine on vestibular disorders of peripheral and central origin. The evaluation of drug efficacy was based on subjective symptoms (vertigo, dizziness) and values of nystagmus parameters in ENG. and stability records made during posturographic tests, before and after drug administration. The regression or moderation of symptoms, such as vertigo and dizziness, was noted as well as the reduction of nystagmus slow phase velocity and the amplitude and the reduction of parameters during posturographic test. The reduction was observed during the treatment, especially during the studies after 4 hours following drug administration. After 6 months, values of the parameters, especially those made during posturographic tests, were close to initial values. The criteria, helpful for diagnosing subjective ailments were discussed with the emphasis placed on the significance of the processes responsible for equilibrium system function return. The review was made of the literature concerning the role of betahistine in the treatment of vestibular disorders.
作者们对倍他司汀治疗外周性和中枢性前庭疾病的效果进行了一项初步研究。药物疗效评估基于主观症状（眩晕、头晕）以及眼震电图（ENG）中眼震参数值，还有姿势描记测试前后给药前后的稳定性记录。观察到眩晕和头晕等症状的减轻或缓解，以及眼震慢相速度、幅度的降低和姿势描记测试期间参数的降低。在治疗期间观察到了这种降低，尤其是在给药后4小时后的研究中。6个月后，参数值，尤其是姿势描记测试中的参数值，接近初始值。讨论了有助于诊断主观疾病的标准，并强调了负责平衡系统功能恢复的过程的重要性。对有关倍他司汀在治疗前庭疾病中作用的文献进行了综述。
