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女童的Legg-Calvé-Perthes病。与男童患病结果的比较。

Legg-Calvé-Perthes disease in girls. A comparison of the results with those seen in boys.

作者信息

Guille J T, Lipton G E, Szöke G, Bowen J R, Harcke H T, Glutting J J

机构信息

Alfred I. du Pont Institute, Wilmington, Delaware 19899, USA.

出版信息

J Bone Joint Surg Am. 1998 Sep;80(9):1256-63. doi: 10.2106/00004623-199809000-00002.

Abstract

We reviewed the records and roentgenograms of all patients with Legg-Calvé-Perthes disease who had been seen at our institution between 1940 and 1996. One hundred and five girls (122 hips) and 470 boys (531 hips) were identified. Thus, 18 per cent of the 575 patients in the present series were girls. Seventeen (16 per cent) of the girls and sixty-one (13 per cent) of the boys had bilateral involvement. Although more girls than boys had severe involvement of the femoral head and the lateral pillar, we could not detect a significant difference between the two groups with respect to the distribution of the involvement of the hips according to the system of Catterall or the lateral pillar classification (p > 0.05, beta = 0.99). Serial roentgenograms that showed all four stages of the disease according to the system of Waldenström were available for fifty-two hips in girls and 184 hips in boys. A review of these roentgenograms revealed that the average ages of the girls at the stages of necrosis, fragmentation, reossification, and remodeling were 6.8, 7.3, 7.9, and 9.5 years, respectively, whereas the average ages of the boys were 6.8, 7.3, 7.9, and 9.9 years, respectively. Girls, however, had closure of the affected proximal femoral physis at an average age of 12.9 years, whereas boys had closure at an average age of 15.8 years. Therefore, girls had a shorter potential period for remodeling of the femoral head (average, 3.4 years) compared with boys (average, 5.9 years). Sixty-four girls (seventy-eight hips) and 363 boys (416 hips) had reached skeletal maturity by the time of the latest follow-up and were evaluated according to the system of Stulberg et al.; we could not detect a significant difference between boys and girls with respect to the distribution of the hips according to this system (p > 0.05, beta = 0.99). Although the numbers were too small for statistical analysis, our findings suggest that boys and girls who have the same Catterall or lateral pillar classification at the time of the initial evaluation can be expected to have similar outcomes according to the classification system of Stulberg et al.

摘要

我们回顾了1940年至1996年间在我们机构就诊的所有患有Legg-Calvé-Perthes病患者的病历和X线片。共识别出105名女孩(122个髋关节)和470名男孩(531个髋关节)。因此,本系列575例患者中18%为女孩。17名(16%)女孩和61名(13%)男孩为双侧受累。尽管股骨头和外侧柱严重受累的女孩比男孩多,但根据Catterall系统或外侧柱分类,我们未发现两组在髋关节受累分布方面存在显著差异(p>0.05,β=0.99)。根据Waldenström系统显示疾病所有四个阶段的系列X线片,女孩有52个髋关节,男孩有184个髋关节。对这些X线片的回顾显示,女孩在坏死、碎裂、再骨化和重塑阶段的平均年龄分别为6.8岁、7.3岁、7.9岁和9.5岁,而男孩的平均年龄分别为6.8岁、7.3岁、7.9岁和9.9岁。然而,女孩受累近端股骨骨骺闭合的平均年龄为12.9岁,而男孩为15.8岁。因此,与男孩(平均5.9岁)相比,女孩股骨头重塑的潜在时间较短(平均3.4岁)。在最近一次随访时,64名女孩(78个髋关节)和363名男孩(416个髋关节)已达到骨骼成熟,并根据Stulberg等人的系统进行评估;根据该系统,我们未发现男孩和女孩在髋关节分布方面存在显著差异(p>0.05,β=0.99)。尽管数量太少无法进行统计分析,但我们的研究结果表明,根据Stulberg等人的分类系统,在初次评估时具有相同Catterall或外侧柱分类的男孩和女孩可能会有相似的结果。

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