[What effects does methadone maintenance treatment have on the rehabilitation of heroin addicts?].

The purpose of the study was to determine the effect of methadone maintenance treatment on heroin addicts. By searching in Medline and Cochrane Library two randomized controlled trials were found where methadone was the main intervention in the rehabilitation of heroin addicts. The trials were found among more than 2,350 articles on various aspects of methadone and were the only ones that met our criteria for inclusion in the study. The two studies comprised 347 participants. Both trials showed that methadone maintenance treatment had a positive effect on continuing participation in the treatment programme. One of the trials also showed that the treatment lowered the rates of opioid and cocaine use. It is alarming that only two randomized controlled trials could be found evaluating the effect of methadone maintenance treatment on the rehabilitation of heroin addicts. No trials demonstrating the effect of the treatment on mortality, crime, prostitution or risk behaviour related to communicable diseases were found.