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[良性纤维性间皮瘤:8例报告]

[Benign fibrous mesothelioma: report of 8 cases].

作者信息

Blanco M, Montero C, Rivas J, Otero I, Yebra M T, Verea H

机构信息

Servicios de Neumología, Hospital Juan Canalejo, La Coruña.

出版信息

Arch Bronconeumol. 1998 Jul-Aug;34(7):361-3. doi: 10.1016/s0300-2896(15)30405-1.

Abstract

Benign fibrous mesothelioma (BFM) is a primary, isolated tumor of the pleura. In 80% of patients the tumor originates in the visceral pleura. BFM is rare and localized malignant mesothelioma, whose prognosis and treatment is significantly different, must be considered as a differential diagnosis. We report 8 cases of BFM excised by thoracotomy. In 6 asymptomatic patients, diagnosis was based on radiological images. One patient with a large tumor suffered dyspnea, acropachia and hypertrophic osteoarthropathy. The last patient experienced long-lasting chest pain even though the tumor was small (3 x 3 x 1 cm). Diagnosis was before thoracotomy in 3 cases, 2 by punch biopsy (tru-cut) and the other by thoracoscopy. The results of pleural fluid analysis were nonspecific in 2 of the 3 cases in which pleural effusion was present. Thoracotomy allowed removal of the entire tumor in all patients.

摘要

良性纤维性间皮瘤(BFM)是一种原发性的、孤立的胸膜肿瘤。80%的患者肿瘤起源于脏层胸膜。BFM较为罕见,必须将其与局部恶性间皮瘤进行鉴别诊断,后者的预后和治疗有显著差异。我们报告8例经开胸手术切除的BFM病例。6例无症状患者的诊断基于影像学检查。1例肿瘤较大的患者出现呼吸困难、杵状指和肥大性骨关节病。最后1例患者尽管肿瘤较小(3×3×1厘米),但经历了长期胸痛。3例患者在开胸手术前确诊,2例通过穿刺活检(切割针活检)确诊,另1例通过胸腔镜确诊。在有胸腔积液的3例患者中,2例的胸腔积液分析结果无特异性。开胸手术使所有患者的肿瘤得以完整切除。

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