Serrano R, Martínez M A, Andrés A, Morales J M, Samartin R
Department of Pathology, Hospital 12 de Octubre, Madrid, Spain.
Histopathology. 1998 Aug;33(2):163-7. doi: 10.1046/j.1365-2559.1998.00462.x.
We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF).
A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial infarction secondary to an isolated coronary vasculitis.
The histopathological findings of the vasculitis were not in keeping with PAN. We postulated that the pathogenesis of vasculitis in FMF is different from that of the classic PAN and might be similar to the mechanism of the serosal inflammation.
我们报告一项病例研究，以阐明结节性多动脉炎（PAN）型血管炎的发病机制，这是家族性地中海热（FMF）的一种罕见并发症。
一名患有淀粉样变性并伴有FMF的女性接受了尸体肾移植，5年后因孤立性冠状动脉血管炎继发急性心肌梗死。
血管炎的组织病理学表现与PAN不符。我们推测FMF中血管炎的发病机制与经典PAN不同，可能与浆膜炎症机制相似。
