Görtz H D, Brigge T
Biological Institute, University of Stuttgart, Germany.
Naturwissenschaften. 1998 Aug;85(8):359-68. doi: 10.1007/s001140050517.
Intracellular bacteria in humans are typically detrimental, and such infections are regarded by the patients as accidental and abnormal. In protozoa it seems obvious that many bacteria have coevolved with their hosts and are well adapted to the intracellular way of life. Manifold interactions between hosts and intracellular bacteria are found, and examples of antibacterial resistance of unknown mechanisms are observed. The wide diversity of intracellular bacteria in protozoa has become particularly obvious since they have begun to be classified by molecular techniques. Some of the bacteria are closely related to pathogens; others are responsible for the production of toxins.
人体内的细胞内细菌通常是有害的,这类感染被患者视为意外和异常情况。在原生动物中,许多细菌显然已经与其宿主共同进化,并很好地适应了细胞内的生活方式。宿主与细胞内细菌之间存在多种相互作用,还观察到了一些机制不明的抗菌抗性实例。自从开始用分子技术对原生动物中的细胞内细菌进行分类以来,其种类的多样性就变得尤为明显。其中一些细菌与病原体密切相关;另一些则会产生毒素。