Klein L T, Frager D, Subramanium A, Lowe F C
Department of Urology, St. Lukes-Roosevelt Hospital Center and Columbia University College of Physicians and Surgeons, New York, New York, USA.
Urology. 1998 Oct;52(4):602-8. doi: 10.1016/s0090-4295(98)00218-0.
Magnetic resonance urography (MRU) is a new technique that uses heavily weighted T2 coronal images with fat suppression pulse. Urine appears white on MRU, resembling an intravenous urogram (IVU). Contrast agents are not necessary. This study describes the use of MRU in the diagnosis and treatment of patients with hematuria.
One hundred six patients with microscopic or gross hematuria and 6 normal volunteers underwent MRU between 1992 and 1995. A modified, heavily weighted T2 technique with intravenous administration of furosemide and ureteral compression was used. Thirty-two patients had other imaging techniques as well for comparison.
MRU provided high-resolution images in almost all cases; 73 (69%) had a normal MRU. Significant findings in the 33 patients with abnormalities included renal cysts in 17 (51%), renal cell carcinoma in 6 (18%), transitional cell carcinoma in 5 (15%), ureteropelvic junction obstruction in 3 (9%), and stones causing obstruction in 6 (18%). Five patients with renal failure also had good visualization of the entire urinary tract. MRU was comparable to other imaging modalities except in identifying nonobstructing calculi.
MRU provides an alternative to conventional imaging of the urinary tract, especially in those patients who have contraindications to ionizing radiation and contrast agents. Improvements in resolution, technique, and cost have to be addressed before it can be used regularly in urologic practice.
磁共振尿路造影(MRU)是一种利用重T2加权冠状位脂肪抑制脉冲成像的新技术。在MRU上尿液呈白色,类似于静脉肾盂造影(IVU)。无需使用造影剂。本研究描述了MRU在血尿患者诊断和治疗中的应用。
1992年至1995年间,106例镜下或肉眼血尿患者及6名正常志愿者接受了MRU检查。采用改良的重T2加权技术,静脉注射呋塞米并进行输尿管压迫。32例患者还接受了其他成像技术检查以作比较。
MRU在几乎所有病例中均能提供高分辨率图像;73例(69%)MRU结果正常。33例异常患者的显著发现包括肾囊肿17例(51%)、肾细胞癌6例(18%)、移行细胞癌5例(15%)、输尿管肾盂连接处梗阻3例(9%)以及结石致梗阻6例(18%)。5例肾衰竭患者的整个尿路也显示良好。除了识别非梗阻性结石外,MRU与其他成像方式相当。
MRU为尿路的传统成像提供了一种替代方法,尤其是对于那些有电离辐射和造影剂禁忌证的患者。在能够常规应用于泌尿外科实践之前,必须解决分辨率、技术和成本方面的改进问题。