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孕期急性故意铁过量摄入

Acute intentional iron overdose in pregnancy.

作者信息

Tran T, Wax J R, Steinfeld J D, Ingardia C J

机构信息

Department of Women's Health Services, Hartford Hospital, Connecticut, USA.

出版信息

Obstet Gynecol. 1998 Oct;92(4 Pt 2):678-80. doi: 10.1016/s0029-7844(98)00214-2.

Abstract

BACKGROUND

Although iron is the second most common overdose agent in pregnancy, the obstetric literature does not reflect current management of this emergency.

CASE

A 27-year-old woman, para 0-3-4-3, at 27 weeks' gestation ingested 24 mg/kg of elemental iron in a suicide attempt. Therapy with crystalloid hydration, gastric lavage, and intravenous deferoxamine chelation treated the overdose without maternal or fetal complications.

CONCLUSION

Pregnancy should not alter therapy for acute iron overdose. Deferoxamine administered in the third trimester is not associated with perinatal complications and is potentially life saving.

摘要

背景

尽管铁是孕期第二常见的过量摄入药物,但产科文献并未反映出对这种紧急情况的当前管理方法。

病例

一名27岁女性,孕0产3流4存3,妊娠27周时为自杀企图摄入了24毫克/千克元素铁。通过晶体液水化、洗胃和静脉注射去铁胺螯合疗法治疗过量摄入,未出现母体或胎儿并发症。

结论

妊娠不应改变急性铁过量的治疗方法。在孕晚期使用去铁胺不会导致围产期并发症,且可能挽救生命。

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