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孕期急性故意铁过量摄入

Acute intentional iron overdose in pregnancy.

作者信息

Tran T, Wax J R, Steinfeld J D, Ingardia C J

机构信息

Department of Women's Health Services, Hartford Hospital, Connecticut, USA.

出版信息

Obstet Gynecol. 1998 Oct;92(4 Pt 2):678-80. doi: 10.1016/s0029-7844(98)00214-2.

DOI:10.1016/s0029-7844(98)00214-2
PMID:9764661
Abstract

BACKGROUND

Although iron is the second most common overdose agent in pregnancy, the obstetric literature does not reflect current management of this emergency.

CASE

A 27-year-old woman, para 0-3-4-3, at 27 weeks' gestation ingested 24 mg/kg of elemental iron in a suicide attempt. Therapy with crystalloid hydration, gastric lavage, and intravenous deferoxamine chelation treated the overdose without maternal or fetal complications.

CONCLUSION

Pregnancy should not alter therapy for acute iron overdose. Deferoxamine administered in the third trimester is not associated with perinatal complications and is potentially life saving.

摘要

背景

尽管铁是孕期第二常见的过量摄入药物,但产科文献并未反映出对这种紧急情况的当前管理方法。

病例

一名27岁女性,孕0产3流4存3,妊娠27周时为自杀企图摄入了24毫克/千克元素铁。通过晶体液水化、洗胃和静脉注射去铁胺螯合疗法治疗过量摄入,未出现母体或胎儿并发症。

结论

妊娠不应改变急性铁过量的治疗方法。在孕晚期使用去铁胺不会导致围产期并发症,且可能挽救生命。

相似文献

1
Acute intentional iron overdose in pregnancy.孕期急性故意铁过量摄入
Obstet Gynecol. 1998 Oct;92(4 Pt 2):678-80. doi: 10.1016/s0029-7844(98)00214-2.
2
Intentional iron overdose in pregnancy--management and outcome.妊娠期故意过量铁摄入——管理与结局
J Emerg Med. 2000 Feb;18(2):225-8. doi: 10.1016/s0736-4679(99)00199-7.
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Haloperidol overdose during pregnancy.孕期氟哌啶醇过量。
Obstet Gynecol. 1997 Oct;90(4 Pt 2):659-61. doi: 10.1016/s0029-7844(97)00395-5.
4
Acute iron intoxication in pregnancy: case report and review of the literature.
Obstet Gynecol. 1992 Sep;80(3 Pt 2):500-1.
5
Iron overdose during pregnancy: successful therapy with deferoxamine.孕期铁过量:去铁胺治疗成功案例
Am J Obstet Gynecol. 1983 Nov 15;147(6):717-8. doi: 10.1016/0002-9378(83)90457-x.
6
Management of acute iron overdose.急性铁过量的管理。
Clin Pharm. 1989 Jun;8(6):428-40.
7
Successful therapy of iron intoxication in pregnancy with intravenous deferoxamine and whole bowel irrigation.静脉注射去铁胺和全肠道灌洗成功治疗妊娠期铁中毒
Vet Hum Toxicol. 1993 Oct;35(5):441-4.
8
[Multidisciplinary treatment of acute iron poisoning due to suicide attempt].[自杀未遂所致急性铁中毒的多学科治疗]
Ugeskr Laeger. 2020 Nov 9;182(46).
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Early endoscopic gastric lavage for acute iron overdose: a novel approach to accidental pill ingestions.急性铁过量中毒的早期内镜下洗胃:一种处理意外吞服药物的新方法。
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[Acute iron poisoning. A case report].[急性铁中毒。病例报告]
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