Yamini D, Vargas H, Bongard F, Klein S, Stamos M J
Department of Surgery, Harbor-University of California at Los Angeles Medical Center, Torrance 90509, USA.
Am Surg. 1998 Oct;64(10):970-5.
Advanced perforated appendicitis with localized findings has classically been treated with either operative therapy or with percutaneous drainage. The role of nonoperative therapy followed by interval appendectomy (IA) remains controversial. We assessed the safety and efficacy of conservative management for perforated appendicitis in a 5-year review of patients treated conservatively for perforated appendicitis with localized abscess or phlegmon. Patients were treated initially with intravenous antibiotics, and CT-guided drainage was used only if the patient failed to improve after 48 to 72 hours. Patients still not improving underwent appendectomy. Patients responding to conservative therapy were recommended IA in 6 to 12 weeks. Sixty-six patients with 54 abscesses and 10 phlegmons were treated. Fifty-one patients (92%) improved without surgery. Only 58 per cent of the abscesses required percutaneous drainage. The mean length of stay for conservative therapy was 7.6 days. Forty-one patients underwent IA with a 10 per cent morbidity and a mean length of stay of 1.4 days. Conservative management of appendicitis with localized perforation or phlegmon is safe and effective. Percutaneous drainage is frequently not required. IA is associated with low morbidity without prolonged hospitalization.
伴有局限性表现的进展期穿孔性阑尾炎传统上采用手术治疗或经皮引流治疗。非手术治疗后行间隔期阑尾切除术(IA)的作用仍存在争议。我们通过对5年来因局限性脓肿或蜂窝织炎而接受保守治疗的穿孔性阑尾炎患者进行回顾,评估了保守治疗穿孔性阑尾炎的安全性和有效性。患者最初接受静脉抗生素治疗,只有在48至72小时后病情无改善时才使用CT引导下引流。病情仍无改善的患者接受阑尾切除术。对保守治疗有反应的患者建议在6至12周内行IA。66例患者中有54个脓肿和10个蜂窝织炎接受了治疗。51例患者(92%)未经手术病情改善。只有58%的脓肿需要经皮引流。保守治疗的平均住院时间为7.6天。41例患者接受了IA,发病率为10%,平均住院时间为1.4天。对局限性穿孔或蜂窝织炎的阑尾炎进行保守治疗是安全有效的。经皮引流常常不需要。IA的发病率低,且不会导致住院时间延长。