先兆子痫中的泌尿生殖系统感染
Urogenital infection in preeclampsia.
作者信息
Hsu C D, Witter F R
机构信息
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT, USA.
出版信息
Int J Gynaecol Obstet. 1995 Jun;49(3):271-5. doi: 10.1016/0020-7292(95)02373-k.
OBJECTIVE
The purpose of this study was to determine whether the incidence of urinary tract infections and postpartum endometritis were increased in preeclamptic pregnancies.
METHOD
We conducted a retrospective study of 13852 pregnant women, using a perinatal database at The Johns Hopkins Hospital, over the past 5 years. The incidence of urinary tract infections and postpartum endometritis was analyzed using the chi-squared test and logistic regression analysis. Statistical significance was set at P < 0.05.
RESULTS
There were 345 (2.5%) mild preeclamptics and 440 (3.2%) severe preeclamptics. The incidence of urinary tract infections and postpartum endometritis in preeclamptic patients was significantly higher than that in non-hypertensive pregnant patients. After controlling for confounding variables, severe preeclampsia was still found to be an independent significant risk factor for both urinary tract infections and postpartum endometritis.
CONCLUSION
Our data show a significant increase in urogenital infection in preeclamptic pregnancy. This may reflect higher rates of underlying renal disease and placental bed abnormalities occurring in preeclampsia.
目的
本研究旨在确定子痫前期妊娠中尿路感染和产后子宫内膜炎的发生率是否增加。
方法
我们使用约翰霍普金斯医院围产期数据库，对过去5年的13852名孕妇进行了一项回顾性研究。使用卡方检验和逻辑回归分析来分析尿路感染和产后子宫内膜炎的发生率。统计学显著性设定为P < 0.05。
结果
有345例（2.5%）轻度子痫前期患者和440例（3.2%）重度子痫前期患者。子痫前期患者中尿路感染和产后子宫内膜炎的发生率显著高于非高血压孕妇。在控制混杂变量后，仍发现重度子痫前期是尿路感染和产后子宫内膜炎的独立显著危险因素。
结论
我们的数据显示子痫前期妊娠中泌尿生殖系统感染显著增加。这可能反映了子痫前期中潜在肾病和胎盘床异常的发生率较高。
Zotero 插件