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Evidence for a pharmacokinetic interaction between itraconazole and tacrolimus in organ transplant patients.器官移植患者中伊曲康唑与他克莫司之间存在药代动力学相互作用的证据。
Br J Clin Pharmacol. 1998 Sep;46(3):271-2. doi: 10.1046/j.1365-2125.1998.00784.x.
2
Interaction between tacrolimus and itraconazole in a heart-lung transplant recipient.一名心肺移植受者中他克莫司与伊曲康唑的相互作用。
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Itraconazole prophylaxis in lung transplant recipients receiving tacrolimus (FK 506): efficacy and drug interaction.接受他克莫司（FK 506）治疗的肺移植受者的伊曲康唑预防：疗效与药物相互作用
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Voriconazole and itraconazole in lung transplant recipients receiving tacrolimus (FK 506): efficacy and drug interaction.伏立康唑和伊曲康唑在接受他克莫司（FK506）治疗的肺移植受者中的疗效和药物相互作用。
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Coadministration of itraconazole and tacrolimus after thoracic organ transplantation.
Transplant Proc. 2001 Feb-Mar;33(1-2):1600-2. doi: 10.1016/s0041-1345(00)02608-7.
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Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient.
Ann Pharmacother. 1999 Oct;33(10):1124-5. doi: 10.1345/aph.18409.
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Tacrolimus dosage requirements in lung transplant recipients receiving antifungal prophylaxis with voriconazole followed by itraconazole: a preliminary prospective study.接受伏立康唑随后伊曲康唑抗真菌预防的肺移植受者的他克莫司剂量需求：一项初步前瞻性研究。
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Tacrolimus/itraconazole interactions: a case report of ABO-incompatible living-related renal transplantation.
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Clinical use and bioavailability of tacrolimus in heart-lung and double lung transplant recipients with cystic fibrosis.他克莫司在患有囊性纤维化的心肺联合移植和双肺移植受者中的临床应用及生物利用度。
Transplant Proc. 1998 Jun;30(4):1519-20. doi: 10.1016/s0041-1345(98)00341-8.

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A case of naganishial pleuritis in a kidney transplant recipient.一名肾移植受者发生长崎胸膜炎的病例。
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Azole interactions with multidrug therapy in pediatric oncology.唑类药物与儿科肿瘤多药治疗的相互作用。
Eur J Clin Pharmacol. 2013 Jan;69(1):1-10. doi: 10.1007/s00228-012-1310-x. Epub 2012 Jun 2.
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Drug interaction between oral solution itraconazole and calcineurin inhibitors in allogeneic hematopoietic stem cell transplantation recipients: an association with bioavailability of oral solution itraconazole.异基因造血干细胞移植受者中口服溶液型伊曲康唑与钙调神经磷酸酶抑制剂之间的药物相互作用：与口服溶液型伊曲康唑生物利用度的关联
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Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions.重症监护病房感染治疗的药代动力学方面：聚焦于药物相互作用。
Clin Pharmacokinet. 2001;40(11):833-68. doi: 10.2165/00003088-200140110-00004.
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Comparative clinical pharmacokinetics of tacrolimus in paediatric and adult patients.他克莫司在儿科和成年患者中的比较临床药代动力学。
Clin Pharmacokinet. 2001;40(4):283-95. doi: 10.2165/00003088-200140040-00004.
6
Clinical experience with itraconazole in systemic fungal infections.伊曲康唑治疗全身性真菌感染的临床经验。
Drugs. 2001;61 Suppl 1:39-47. doi: 10.2165/00003495-200161001-00004.
7
Effects of the antifungal agents on oxidative drug metabolism: clinical relevance.抗真菌药物对氧化药物代谢的影响：临床相关性。
Clin Pharmacokinet. 2000 Feb;38(2):111-80. doi: 10.2165/00003088-200038020-00002.

Evidence for a pharmacokinetic interaction between itraconazole and tacrolimus in organ transplant patients.

作者信息

Billaud E M, Guillemain R, Tacco F, Chevalier P

出版信息

Br J Clin Pharmacol. 1998 Sep;46(3):271-2. doi: 10.1046/j.1365-2125.1998.00784.x.

DOI:10.1046/j.1365-2125.1998.00784.x
PMID:9764970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1873673/
Abstract
摘要