Pei Z M, Ghassemian M, Kwak C M, McCourt P, Schroeder J I
Department of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, CA 92093-0116, USA.
Science. 1998 Oct 9;282(5387):287-90. doi: 10.1126/science.282.5387.287.
Desiccation of plants during drought can be detrimental to agricultural production. The phytohormone abscisic acid (ABA) reduces water loss by triggering stomatal pore closure in leaves, a process requiring ion-channel modulation by cytoplasmic proteins. Deletion of the Arabidopsis farnesyltransferase gene ERA1 or application of farnesyltransferase inhibitors resulted in ABA hypersensitivity of guard cell anion-channel activation and of stomatal closing. ERA1 was expressed in guard cells. Double-mutant analyses of era1 with the ABA-insensitive mutants abi1 and abi2 showed that era1 suppresses the ABA-insensitive phenotypes. Moreover, era1 plants exhibited a reduction in transpirational water loss during drought treatment.
干旱期间植物脱水会对农业生产造成损害。植物激素脱落酸（ABA）通过触发叶片气孔关闭来减少水分流失，这一过程需要细胞质蛋白对离子通道进行调节。拟南芥法尼基转移酶基因ERA1缺失或应用法尼基转移酶抑制剂会导致保卫细胞阴离子通道激活和气孔关闭对ABA超敏感。ERA1在保卫细胞中表达。era1与ABA不敏感突变体abi1和abi2的双突变分析表明，era1抑制了ABA不敏感表型。此外，era1植株在干旱处理期间蒸腾水分流失减少。
