耻垢分枝杆菌mIHF基因的鉴定
Characterization of the mIHF gene of Mycobacterium smegmatis.
作者信息
Pedulla M L, Hatfull G F
机构信息
Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
出版信息
J Bacteriol. 1998 Oct;180(20):5473-7. doi: 10.1128/JB.180.20.5473-5477.1998.
Abstract
Integration of mycobacteriophage L5 requires the mycobacterial integration host factor (mIHF) in vitro. mIHF is a 105-residue heat-stable polypeptide that is not obviously related to HU or any other small DNA-binding proteins. mIHF is most abundant just prior to entry into stationary phase and is essential for the viability of Mycobacterium smegmatis.
摘要
分枝杆菌噬菌体L5的整合在体外需要分枝杆菌整合宿主因子（mIHF）。mIHF是一种由105个氨基酸残基组成的热稳定多肽，与HU或任何其他小的DNA结合蛋白没有明显关系。mIHF在进入稳定期之前最为丰富，对耻垢分枝杆菌的生存能力至关重要。
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