Kormanik P A, Chamberlain M C
Bone Marrow Transplant Service, University of California, San Diego, USA.
Oncol Nurs Forum. 1998 Sep;25(8):1355-62; quiz 1363-4.
PURPOSE/OBJECTIVES: To review the pathophysiology, diagnosis, and clinical treatment of leptomeningeal metastasis.
Published articles, abstracts, and book chapters.
Leptomeningeal metastasis is an increasingly seen complication of cancer. Treatment is intensive and may increase survival from four to five weeks without treatment to an average of six months. Clinical management and treatment of these patients is complex and best accomplished by a multi-disciplinary healthcare team.
Information regarding the anatomy, pathophysiology, treatment, and treatment complications can facilitate the care of patients with leptomeningeal metastasis.
Nursing interventions should focus on patient and family education about the disease process, side-effects of treatment, and early identification of disease progression.
目的/目标：回顾柔脑膜转移的病理生理学、诊断及临床治疗。
已发表的文章、摘要及书籍章节。
柔脑膜转移是一种越来越常见的癌症并发症。治疗力度大，可使未经治疗时平均存活四至五周提高到平均六个月。这些患者的临床管理和治疗很复杂，最好由多学科医疗团队来完成。
有关解剖学、病理生理学、治疗及治疗并发症的信息有助于护理柔脑膜转移患者。
护理干预应侧重于对患者及家属进行疾病过程、治疗副作用及疾病进展早期识别方面的教育。
