妊娠晚期及分娩时人体血浆中前列腺素 F 水平（作者译）
[Prostaglandin-F-levels in human plasma during late pregnancy and labour (author's transl)].
作者信息
Zahradnik H P, Geisthövel F, Weitzell R, Breckwoldt M
出版信息
Geburtshilfe Frauenheilkd. 1976 Sep;36(9):710-14.
The concentrations of prostaglandin F-equivalents were measured in peripheral plasma during labour at a cervical dilatation of 5 cm and at complete dilatation. After purification, extraction and chromatography the PGF-equivalents were measured radioimmunologically. The intraassay variation was 1.5%, the interassay variation 3.5%. The specificity for PGF was 96-98%. Logit/log transformation of the standardcurve yielded a sensitivity of the assay of 120 pg. At cervical dilatation of 5 cm PGF-equivalents varied between 1300 and 3200 pg/ml plasma. At complete dilatation values changed between 1200 and 5400 pg/ml. These fluctuations correlate timedepending to the uterine contractions recorded and may be interpreted as a result of uterine PGF-release.
在宫颈扩张5厘米时及完全扩张时，测量分娩期间外周血浆中前列腺素F等效物的浓度。经过纯化、提取和色谱分析后，采用放射免疫法测定前列腺素F等效物。批内变异为1.5%，批间变异为3.5%。对前列腺素F的特异性为96 - 98%。标准曲线经对数几率/对数转换后，该检测方法的灵敏度为120皮克。在宫颈扩张5厘米时，前列腺素F等效物在血浆中的浓度在1300至3200皮克/毫升之间变化。在完全扩张时，数值在1200至5400皮克/毫升之间变化。这些波动与记录的子宫收缩在时间上相关，可能被解释为子宫释放前列腺素F的结果。
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