Fiedler G, Arnold M, Maldener I
Universität Regensburg, Lehrstuhl für Zellbiologie und Pflanzenphysiologie, 93040 Regensburg, Germany.
Biochim Biophys Acta. 1998 Oct 15;1375(1-2):140-3. doi: 10.1016/s0005-2736(98)00147-3.
The devBCA gene cluster (dev for development), shown to be essential for envelope formation in heterocysts of Anabaena sp. strain PCC 7120, was identified in the gene bank of a second heterocyst-forming strain, Anabaena variabilis ATCC 29413. Sequence and structural organization of the three genes, encoding subunits of a presumptive ABC transporter, were nearly identical in both strains. Mutants of A. variabilis defective in the devA gene were constructed. As devA mutants of Anabaena 7120, A. variabilis mutants were unable to grow on N2 as sole nitrogen source due to incomplete differentiation of heterocysts.
devBCA基因簇（dev代表发育），已证明其对鱼腥藻属PCC 7120菌株异形胞的包膜形成至关重要，在另一种形成异形胞的菌株多变鱼腥藻ATCC 29413的基因库中被鉴定出来。编码一种假定ABC转运蛋白亚基的三个基因的序列和结构组织在这两种菌株中几乎相同。构建了devA基因有缺陷的多变鱼腥藻突变体。与鱼腥藻7120的devA突变体一样，多变鱼腥藻突变体由于异形胞分化不完全而无法以N2作为唯一氮源生长。
