Turner R J, Sviland L, Lawrence C M
Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne NE1 4LP, U.K.
Br J Dermatol. 1998 Aug;139(2):295-8. doi: 10.1046/j.1365-2133.1998.02370.x.
A man with a 15-year history of non-Hodgkin's lymphoma presented with disseminated herpes zoster which initially responded to aciclovir. This was shortly followed by an acute exacerbation in the sites previously affected which was apparently resistant to antiviral therapy. Biopsy revealed a dense monomorphic lymphocytic infiltrate below active herpes zoster which had the same morphology and immunoreactivity as the underlying lymphoma. His clinical condition resolved with further chemotherapy for his lymphoma and continued treatment with aciclovir.
一名有15年非霍奇金淋巴瘤病史的男性患者出现播散性带状疱疹，最初对阿昔洛韦有反应。但随后不久，先前受累部位出现急性加重，显然对抗病毒治疗耐药。活检显示，在活动性带状疱疹下方有密集的单形性淋巴细胞浸润，其形态和免疫反应性与潜在的淋巴瘤相同。他的临床症状通过针对淋巴瘤的进一步化疗以及继续使用阿昔洛韦治疗后得到缓解。
