Denoble V J, Begleiter H
Pharmacol Biochem Behav. 1978 Apr;8(4):391-7. doi: 10.1016/0091-3057(78)90075-8.
Responding by 4 monkeys was maintained under a fixed ratio 10 (FR 10) schedule for either food, intravenous sucrose or alcohol. The 20 hr sessions were divided so that food was available during hours 1, 6, 11, 16 and alcohol or sucrose during hours 2-5, 7-10, 12-15, and 17-20. All animals failed to maintain responding for isocaloric sucrose but continued to respond for food during those sessions. Responding under alcohol conditions was positively accelerated in 2 animals that were not previously exposed to alcohol, whereas prior exposure to alcohol produced maximal response rates during the first alcohol test session. The effects of alcohol in all monkeys were to suppress responding maintained by food and this suppression could not be produced with programmed infusions of isocaloric sucrose.
4只猴子的反应在固定比率10（FR 10）的时间表下维持，以获取食物、静脉注射蔗糖或酒精。20小时的实验时段被划分，使得在第1、6、11、16小时可获取食物，在第2 - 5、7 - 10、12 - 15和17 - 20小时可获取酒精或蔗糖。所有动物均未能维持对等热量蔗糖的反应，但在这些时段中仍继续对食物做出反应。在2只先前未接触过酒精的动物中，酒精条件下的反应呈正加速，而先前接触过酒精的动物在首次酒精测试时段产生了最大反应率。酒精对所有猴子的影响是抑制由食物维持的反应，而等热量蔗糖的程序化输注无法产生这种抑制作用。
