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一项关于两种新生儿无菌尿液采集方法的随机对照试验。

A randomized controlled trial of two methods for collection of sterile urine in neonates.

作者信息

Tobiansky R, Evans N

机构信息

Department of Neonatal Medicine. Royal Prince Alfred Hospital and University of Sydney, Camperdown, NSW, Australia.

出版信息

J Paediatr Child Health. 1998 Oct;34(5):460-2. doi: 10.1046/j.1440-1754.1998.00272.x.

Abstract

OBJECTIVE

To test whether urethral catheterization (UC) is better than suprapubic bladder aspiration (SPA) as a method for collection of sterile urine in neonates.

METHODS

Thirty-three babies, requiring sterile collection of urine, were randomly assigned to either urethral catheterization (n=16), median gestation 28+/-3.9 weeks, median birth weight 968 g (range 650-4100) or SPA (n=17), median gestation 26+/-5.6 weeks, median birth weight 926 g (range 771-4070). The primary outcome was success in obtaining urine. Secondary outcomes were complications and urine culture results.

RESULTS

Some urine was obtained in 11 (64.7%) babies in the SPA group and in 13 (81.2%) babies in the catheter group. Sufficient urine for analysis (>0.5 ml) was obtained in 10 (58.8%) in the SPA group versus 5 (31.2%) babies in the catheter group. There were more contaminated specimens in the catheter group but this was not significant in this small study.

CONCLUSIONS

In this small randomized controlled trial urethral catheterization offered no significant advantage over SPA.

摘要

目的

测试在新生儿中,作为收集无菌尿液的一种方法,经尿道导尿(UC)是否优于耻骨上膀胱穿刺抽吸(SPA)。

方法

33名需要无菌采集尿液的婴儿被随机分为经尿道导尿组(n = 16),中位孕周28±3.9周,中位出生体重968克(范围650 - 4100克)或耻骨上膀胱穿刺抽吸组(n = 17),中位孕周26±5.6周,中位出生体重926克(范围771 - 4070克)。主要结局是成功获取尿液。次要结局是并发症和尿液培养结果。

结果

耻骨上膀胱穿刺抽吸组11名(64.7%)婴儿获取了一些尿液,导尿组13名(81.2%)婴儿获取了尿液。耻骨上膀胱穿刺抽吸组10名(58.8%)婴儿获取了足够用于分析的尿液(>0.5毫升),而导尿组为5名(31.2%)婴儿。导尿组污染标本更多,但在这项小型研究中差异无统计学意义。

结论

在这项小型随机对照试验中,经尿道导尿相对于耻骨上膀胱穿刺抽吸无显著优势。

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