Grolleau J L, Lanfrey E, Zeybeck C, Chavoin J P, Costagliola M
Service de Chirurgie Plastique Réparatrice et Esthétique, CHU de Toulouse, Hôpital Rangueil, Toulouse, France.
Ann Chir Plast Esthet. 1997 Dec;42(6):609-14.
Deferred prosthetic breast reconstruction after skin expansion is considered to be difficult after radiotherapy. The authors report a series of 14 cases of reconstruction after radiotherapy, compared with 6 cases of reconstruction without radiotherapy. They reported a similar quality of results after radiotherapy not including irradiation of the chest wall and in the absence of radiotherapy (p = 0.742). On the other hand, a significant deterioration of the results was observed when radiotherapy included chest wall irradiation (p = 0.0015). Finally, no direct correlation was observed between the macroscopic appearance of the skin and presence or absence of a history of irradiation of the chest wall. They conclude that the indications for reconstruction by tissue expansion after radiotherapy must be based more on the irradiation protocol than on the macroscopic appearance of the skin.
放疗后进行延迟性乳房假体再造被认为具有挑战性。作者报告了14例放疗后乳房再造病例，并与6例未接受放疗的乳房再造病例进行了对比。他们指出，在未对胸壁进行放疗的情况下，放疗后的乳房再造效果与未接受放疗的情况相似（p = 0.742）。另一方面，当放疗包括胸壁照射时，效果显著变差（p = 0.0015）。最后，皮肤的宏观外观与胸壁是否接受过放疗之间未发现直接关联。他们得出结论，放疗后通过组织扩张进行乳房再造的适应症应更多地基于放疗方案，而非皮肤的宏观外观。
