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[带血管蒂骨膜瓣围绕珊瑚植入物管状化后的成骨能力。绵羊实验研究]

[Osteogenic capacity of a vascularized periosteal flap tubulized around a coral implant. Experimental study on sheep].

作者信息

Payement G, Therin M, Dansard C, Delay E

机构信息

Service de Chirurgie Plastique, Chirurgie Maxillo-Faciale et Stomatologie, Lyon, France.

出版信息

Ann Chir Plast Esthet. 1996 Dec;41(6):651-9.

PMID:9768174
Abstract

The objective of this study was to evaluate the osteogenic capacities of a vascularized periosteal flap reinforced by a bone substitute, coral, to validate the possibility of creating prefabricated bone flaps with shapes adapted to a recipient zone, while limiting the donor site sequelae. 24 periosteal flaps, with preserved vascular pedicles, were raised from the medial femoral epiphyses of 12 ewes. In the same animal, these flaps were reinforced with a cylinder of coral and a cylinder of autologous graft. After implantation for 2 or 8 weeks depending on the animal, the flaps were submitted to histopathological and histomorphometric examination. The results of this examination demonstrated a similar course of the flaps regardless of the type of reinforcement, both in terms of implant resorption and the quantity of newly formed bone.

摘要

本研究的目的是评估用骨替代物珊瑚增强的带血管骨膜瓣的成骨能力,以验证制作形状适合受区的预制骨瓣的可能性,同时限制供区后遗症。从12只母羊的股骨内侧骨骺处掀起24个保留血管蒂的骨膜瓣。在同一只动物身上,用珊瑚圆柱体和自体移植物圆柱体增强这些骨膜瓣。根据动物情况植入2周或8周后,对骨膜瓣进行组织病理学和组织形态计量学检查。该检查结果表明,无论增强类型如何,骨膜瓣在植入物吸收和新形成骨的数量方面都有相似的过程。

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