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[西恩富戈斯省圣路易斯脑炎、东部马脑炎和西部马脑炎的监测]

[Surveillance of St. Louis encephalitis, Eastern equine and Western equine in the province of Ciego de Avila].

作者信息

Pelegrino J L, Suárez M, Guzmán M G, Vázquez S, Benítez N R

机构信息

Instituto de Medicina Tropical Pedro Kouri.

出版信息

Rev Cubana Med Trop. 1996;48(2):109-13.

PMID:9768280
Abstract

Serological studies were carried out using the haemagglutination inhibition and neutralization tests so as to know the circulation dynamics of some arboviruses with the use of Western and Eastern equine encephalitis antigens and St Louis encephalitis antigens in human serum from sound and symptomatic individuals, as well as from sentinel birds, between 1987 and 1991, and during 1994. 1.7% of the asymptomatic subjects tested presented neutralizing antibodies to to Eastern equine and 4.8% to St Louis encephalitis. 16 patients with seroconversion by haemagglutination inhibition to St Louis virus were detected. Surveillance of sentinel birds showed that during 1988, 1989, and 1994. St. Louis circulated in the municipalities of Morón, Bolivia and Chambas; whereas in the latter the Eastern equine encephalitis circulated in 1988 and 1989. Antibodies to Western equine encephalitis were detected in sound individuals by haemagglutination inhibition due seemingly to heterologous antibodies, since there were no neutralizing antibodies against this virus.

摘要

采用血凝抑制试验和中和试验进行血清学研究,以便利用西方马脑炎、东方马脑炎抗原以及圣路易斯脑炎抗原,了解1987年至1991年以及1994年期间健康个体、有症状个体以及哨兵鸟类血清中某些虫媒病毒的传播动态。检测的无症状受试者中,1.7%呈现针对东方马脑炎的中和抗体,4.8%呈现针对圣路易斯脑炎的中和抗体。检测到16例通过血凝抑制试验发生圣路易斯病毒血清转化的患者。哨兵鸟类监测显示,1988年、1989年和1994年期间,圣路易斯脑炎在玻利维亚莫龙市和钱巴斯市传播;而在钱巴斯市,1988年和1989年有东方马脑炎传播。通过血凝抑制试验在健康个体中检测到针对西方马脑炎的抗体,这似乎是由于异源抗体所致,因为不存在针对该病毒的中和抗体。

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