Ashraf S I, Ip Y T
Program in Molecular Medicine, University of Massachusetts Medical Center, Worcester 01605, USA.
Curr Biol. 1998 Sep 24;8(19):R683-6. doi: 10.1016/s0960-9822(98)70435-x.
It is becoming increasingly clear that chromatin modification plays a fundamental part in transcriptional control. Recent studies provide new insights into how transcriptional repressors, in addition to blocking activators, may recruit repression complexes that include chromatin modification factors.
越来越明显的是,染色质修饰在转录调控中起着基础性作用。最近的研究为转录抑制因子除了阻断激活因子之外,如何招募包括染色质修饰因子在内的抑制复合物提供了新的见解。