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国产玉米淀粉在碳酸钙片生产中的应用

[Use of domestically produced corn starch in the manufacture of calcium carbonate tablets].

作者信息

Gazikalović E, Obrenović D, Nidzović Z, Toskić-Radojicić M

出版信息

Vojnosanit Pregl. 1998 Jul-Aug;55(4):407-10.

PMID:9769742
Abstract

The results of the testing of calcium carbonate tablets, compounded with starch as the binding and decay substance are presented. The content of calcium carbonate in the tablets, as well as the mass varying, solidity, prodigality and aptness to decay were determined. The best properties were observed in the tablets with 15% starch mucilage, added suddenly, in the whole amount, to the prepared mixture of calcium carbonate and lactose. This procedure is fast and simple, and compound tablets of calcium carbonate are of regulated quality.

摘要

本文展示了以淀粉作为黏合剂和崩解剂的碳酸钙片剂的测试结果。测定了片剂中碳酸钙的含量以及质量变化、硬度、溶出度和崩解性。在将15%淀粉糊剂一次性全部加入制备好的碳酸钙与乳糖混合物的片剂中观察到了最佳性能。该方法快速简便,且碳酸钙复方片剂质量可控。

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引用本文的文献

1
Evaluation of quick disintegrating calcium carbonate tablets.速崩解碳酸钙片的评估
AAPS PharmSciTech. 2000 Jul 2;1(3):E20. doi: 10.1208/pt010320.