Pinto R J
Holy Family Hospital, Bandra (W), Mumbai, India.
Indian J Med Sci. 1998 Feb;52(2):49-54.
Contrary to popular belief that coronary heart disease (CHD) is uncommon in developing countries, Asian Indians have among the highest prevalence of CHD. Analysis of numerous studies have now revealed that the usual risk factors i.e. hypertension, hypercholesterolemia, obesity, smoking and a family history of CHD, are not common among South Asians. Rather, they possess a different risk factor profile characterized by high triglycerides, low HDL, glucose intolerance, insulin resistance, abdominal obesity and increased lipoprotein(a) levels. On account of this difference and the alarming explosion of CHD in India, guidelines for prevention of CHD as laid down by the American Heart Association may not be applicable in our population. A judicious diet incorporating commonly used Indian food items and regular exercise will go a long way in effective primary prevention.
与普遍认为冠心病（CHD）在发展中国家不常见的观点相反，亚洲印度人患冠心病的患病率是最高的之一。对众多研究的分析现已表明，常见的危险因素，即高血压、高胆固醇血症、肥胖、吸烟和冠心病家族史，在南亚人中并不常见。相反，他们具有不同的危险因素特征，其特点是甘油三酯高、高密度脂蛋白低、葡萄糖不耐受、胰岛素抵抗、腹部肥胖和脂蛋白（a）水平升高。由于这种差异以及印度冠心病令人震惊的激增，美国心脏协会制定的冠心病预防指南可能不适用于我国人群。将常用的印度食品纳入其中的明智饮食和定期锻炼对有效的一级预防大有帮助。
