Patel N B, Jindal M N, Patel V K
Indian J Physiol Pharmacol. 1976 Jul-Sep;20(3):172-6.
The effects of a new series of glutarimide compounds have been studied in acetylcholine induced auricular fibrillation in anaesthetized cats and epinephrine induced ventricular arrhythmmias in conscious pigeons. Some of the compounds showed varying degree of protective action against experimental arrhythmias. However these compounds were found to be less potent than quinidine. The mechanism of antiarrhythmic action has been discussed.
已对一系列新型戊二酰亚胺化合物在麻醉猫的乙酰胆碱诱发心房颤动以及清醒鸽子的肾上腺素诱发室性心律失常中的作用进行了研究。其中一些化合物对实验性心律失常表现出不同程度的保护作用。然而,发现这些化合物的效力低于奎尼丁。文中还讨论了其抗心律失常作用的机制。