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[血清和精浆中睾酮对生育期男性及精子发生障碍患者抗雌激素刺激试验的反应]

[Testosterone response (in blood serum and seminal plasma) to anti-estrogen stimulation test in fertile men and patients with disturbances of spermatogenesis].

作者信息

Medraś M, Kiełkiewicz D

机构信息

Katedry i Kliniki Endokrynologii AM we Wrocławiu.

出版信息

Pol Merkur Lekarski. 1998 Apr;4(22):205-7.

PMID:9770998
Abstract

Testosterone concentrations in blood serum and seminal plasma in basic conditions and in antiestrogen test (Clostilbegyt 100 mg daily for 10 days) were evaluated for 21 fertile males, 24 males with normogonadotropic oligozoospermia and 25 azoospermia patients. Average output testosterone concentration in blood serum of the analysed groups did not differ statistically significantly, but in antiestrogen test it increased statistically significantly. Average output testosterone concentration in semen plasma in fertile men was 0.66 +/- 0.26 ng/ml (about 10 times lower than in blood serum) and idiopatic oligozoospermic patients had a half of this number. Clostilbegyt test caused increase of testosterone concentration in semen plasma in all groups (except for normospermic) what proves the relation of hormonal reactions observed in blood serum with the ones in semen plasma.

摘要

对21名有生育能力的男性、24名促性腺激素正常的少精子症男性和25名无精子症患者,评估了基础条件下以及抗雌激素试验(每日服用100毫克克罗米芬,持续10天)时血清和精浆中的睾酮浓度。分析组血清中睾酮的平均输出浓度在统计学上没有显著差异,但在抗雌激素试验中,其有统计学显著升高。有生育能力男性精浆中睾酮的平均输出浓度为0.66±0.26纳克/毫升(约比血清中低10倍),特发性少精子症患者的这一数值为其一半。克罗米芬试验使所有组(除了精子正常的组)精浆中睾酮浓度升高,这证明了血清中观察到的激素反应与精浆中的激素反应之间的关系。

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