Hop J W, Brilstra E H, Rinkel G J
University Department of Neurology, Utrecht, The Netherlands.
J Neurol Neurosurg Psychiatry. 1998 Oct;65(4):590-3. doi: 10.1136/jnnp.65.4.590.
Although long term outcome of patients with perimesencephalic haemorrhage, a benign subset of subarachnoid haemorrhage, is excellent, some patients report an episode of amnesia for the first hours to days after the ictus. The relation between the occurrence of amnesia and the size of the ventricles on CT, including the temporal horns, were studied in patients with perimesencephalic haemorrhage.
Twenty seven consecutive patients with perimesencephalic haemorrhage were asked about the occurrence of amnesia. Age adjusted bicaudate indices and third ventricle sizes were calculated. Linear measurements of the temporal horn were taken in three directions: anterior-posterior, medial-lateral, and oblique. Additionally, enlargement of the temporal horns was assessed with the "naked eye".
Ten of the 27 patients reported an episode of transient amnesia; in these patients the mean sizes of the temporal horns were larger than in patients without amnesia, ranging from a factor of 1.7 for the medial-lateral measurement to a factor of 2.3 for the anterior-posterior measurement. Most of the patients with amnesia had relative bicaudate indices and relative third ventricle sizes> 1, and all had enlarged temporal horns at "naked eye" assessment.
About one third of patients with perimesencephalic haemorrhage have an episode of amnesia shortly after the bleed. The occurrence of amnesia is associated with enlargement of the temporal horns, and might be explained by temporary hippocampal dysfunction.
虽然脑周出血（蛛网膜下腔出血的一种良性亚型）患者的长期预后良好，但一些患者在发病后的最初数小时至数天会出现失忆发作。我们研究了脑周出血患者失忆的发生与CT上脑室大小（包括颞角）之间的关系。
询问了连续27例脑周出血患者是否发生失忆。计算了年龄校正后的双尾状核指数和第三脑室大小。从三个方向对颞角进行线性测量：前后方向、内外侧方向和斜向。此外，用“肉眼”评估颞角的扩大情况。
27例患者中有10例报告有短暂失忆发作；在这些患者中，颞角的平均大小比没有失忆的患者更大，内外侧测量的系数为1.7，前后测量的系数为2.3。大多数失忆患者的相对双尾状核指数和相对第三脑室大小>1，并且在“肉眼”评估中均有颞角扩大。
约三分之一的脑周出血患者在出血后不久会出现失忆发作。失忆的发生与颞角扩大有关，可能是由海马体暂时性功能障碍所解释。
