[Mechanisms of the calcium influx across the plasma membrane].

The Ca2+ influx is mainly mediated by voltage-dependent Ca2+ channels and store depletion-dependent Ca2+ channels. The former, which mainly acts to regulate Ca2+ influx in excitable cells, is relatively clear; However, the later, which mainly functions in nonexcitable cells, remains enigmatically complicated. Following activation of the intracellular Ca2+ store, the depletion of the store provides a signal for activating Ca2+ entry across the plasma membrane via presently unknown mechanisms. This paper reviews the rapid progress in this field.