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[The role of adenosine in the central nervous system].

作者信息

Zhang W L, Lu G W

机构信息

Department of Neurobiology, Capital University of Medical Sciences, Beijing.

出版信息

Sheng Li Ke Xue Jin Zhan. 1996 Oct;27(4):313-8.

PMID:9772380
Abstract

Adenosine is one of the normal elements in body fluid including extracellular fluid within the CNS. Its normal level is 0.03-0.3 mumol/L. When ATP's metabolism loses balance, for example, during ischemia, the level of adenosine increases dramatically, may reach as much as 1000 times of the normal. Adenosine plays many physiological and pathological roles in CNS via its receptors. It is recognized as an inhibitory neuromodulator playing a neuroprotective role in CNS.

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