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一种新型房水引流植入物治疗难治性青光眼的短期临床研究

Short-term clinical study on a new aqueous humor drainage implant for refractory glaucoma.

作者信息

Duan X, Jiang Y, Xiong X

机构信息

Department of Ophthalmology, Second Affiliated Hospital of Hunan Medical University, Changsha, China.

出版信息

Chin Med J (Engl). 1997 Nov;110(11):879-82.

PMID:9772423
Abstract

OBJECTIVE

To investigate the therapeutic effect of a new aqueous humor drainage (HAD) implant made in China for the treatment of refractory glaucoma.

METHODS

The implant was designed by ourselves and manufactured by Beijing Rubber Products Design and Research Institute. From July, 1993 to September, 1995, we observed 40 patients (41 eyes) with refractory glaucoma treated by implantation surgery, including 16 eyes with neovascular glaucoma (NVG) and 25 eyes with non-neovascular glaucoma (NNVG).

RESULTS

The mean period of postoperative follow-up was 9.2 (range, from 3-27) months, the intraocular pressure (IOP) was lowered from preoperative 7.20 +/- 1.51 kPa to postoperative 2.40 +/- 1.33 kPa in NVG group and from preoperative 6.27 +/- 1.07 kPa to postoperative 2.00 +/- 2.93 kPa in NNVG group. The success rate was 81% in NVG group and 84% in NNVG group. The common postoperative complications were flat anterior chamber, hyphema and choroidal detachment.

CONCLUSIONS

Our newly designed aqueous humor drainage implant is an economical implant in China and one of the alternative and effective methods for the treatment of refractory glaucoma. It can be widely used in clinics.

摘要

目的

探讨国产新型房水引流(HAD)植入物治疗难治性青光眼的疗效。

方法

该植入物由我们自行设计,北京橡胶制品设计研究院制造。1993年7月至1995年9月,我们观察了40例(41只眼)难治性青光眼患者接受植入手术治疗,其中新生血管性青光眼(NVG)16只眼,非新生血管性青光眼(NNVG)25只眼。

结果

术后平均随访时间为9.2(范围3 - 27)个月,NVG组眼压从术前的7.20±1.51kPa降至术后的2.40±1.33kPa,NNVG组眼压从术前的6.27±1.07kPa降至术后的2.00±2.93kPa。NVG组成功率为81%,NNVG组成功率为84%。常见的术后并发症有浅前房、前房积血和脉络膜脱离。

结论

我们新设计的房水引流植入物是中国一种经济的植入物,是治疗难治性青光眼的替代有效方法之一,可在临床上广泛应用。

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