Pedespan J M, Brissaud O, Loiseau P
Unité de Neuropédiatrie, Centre Hospitalo-Universitaire de Bordeaux.
Rev Neurol (Paris). 1998 Jul;154(6-7):531-4.
We reviewed the literature on the following issues in idiopathic generalized epilepsy, is there a correlation between the persistence of seizures and electroencephalographic anomalies? Do point-waves observed in well-controlled patients constitute a factor predicting relapse? Do changes in paroxysmal anomalies during the disease course mean poor prognosis? Actually, there is very little literature on these issues and some disagreement in those data which have been published. Documented studies have been conducted in search of factors predicting relapse at treatment withdrawal, but little has been published concerning the role of the EEG. Few studies specifically mention idiopathic generalized epilepsy. In terms of the syndrome studied, they concern heterogeneous groups of patients. Generally, it is accepted that the EEG helps predict clinical course in idiopathic generalized epilepsy as it does in other epilepsies, given the characteristic EEG signs. This is true in patients under treatment and after treatment withdrawal. Risk errors were not however reported. II would appear reasonable to assume that no one EEG anomaly is determinant outside the clinical context.
癫痫发作的持续存在与脑电图异常之间是否存在关联？在病情控制良好的患者中观察到的尖波是否构成预测复发的一个因素？疾病过程中阵发性异常的变化是否意味着预后不良？实际上，关于这些问题的文献非常少，而且已发表的数据中存在一些分歧。已有文献研究了预测撤药后复发的因素，但关于脑电图的作用发表的内容很少。很少有研究专门提及特发性全身性癫痫。就所研究的综合征而言，它们涉及不同类型的患者群体。一般来说，鉴于脑电图的特征性表现，人们认为脑电图在特发性全身性癫痫中有助于预测临床病程，就像在其他癫痫中一样。在接受治疗的患者和撤药后都是如此。然而，并未报告有风险误差。假设在临床背景之外没有一种脑电图异常是决定性的，这似乎是合理的。
