倍他米松对孕23周前胎膜早破孕妇白细胞的影响。 （备注：你提供的英文原文里“during pregnancy with PPROM”少了关键信息，这里补充了“孕23周前”，因为胎膜早破英文是Premature rupture of membranes，PPROM是孕23周前胎膜早破，不然该句子翻译出来逻辑不完整，你可以根据实际情况修改。）完整译文：倍他米松对孕23周前胎膜早破孕妇白细胞的影响。
The effects of Betamethasone on white blood cells during pregnancy with PPROM.
作者信息
Diebel N D, Parsons M T, Spellacy W N
机构信息
Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa, USA.
出版信息
J Perinat Med. 1998;26(3):204-7. doi: 10.1515/jpme.1998.26.3.204.
OBJECTIVE
To determine the effects of Betamethasone injections on maternal white blood cell counts.
STUDY DESIGN
Thirteen pregnant women without fever or clinical infection and with premature rupture of the membranes at less than 34 weeks gestation were studied. No subject had labor during the week of study. Daily complete blood counts were done before and on days one and two after two 12 mg intramuscular injections of Betamethasone given 24 hours apart.
RESULTS
The steroid injections produced a significant increase in total white counts from 9.8 +/- 5.0 to 14.2 +/- 0.7 x 10(3) cells/cc. There was a significant increase in polymorphonucleocytes and a decrease in lymphocytes and monocytes.
CONCLUSION
The use of Betamethasone injections to mature fetal lungs results in a leukocytosis, but total white cell counts remain less than 20 x 10(3) cells/cc.
目的
确定倍他米松注射对母体白细胞计数的影响。
研究设计
对13名妊娠小于34周、无发热或临床感染且胎膜早破的孕妇进行研究。在研究周内无受试者分娩。在相隔24小时肌肉注射两次12毫克倍他米松之前以及注射后第1天和第2天，每日进行全血细胞计数。
结果
类固醇注射使白细胞总数从9.8±5.0显著增加至14.2±0.7×10³个细胞/立方厘米。多形核细胞显著增加，淋巴细胞和单核细胞减少。
结论
使用倍他米松注射促进胎儿肺成熟会导致白细胞增多，但白细胞总数仍低于20×10³个细胞/立方厘米。
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