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[哇巴因对7例杜兴氏肌营养不良症患者红细胞电泳迁移率的影响]

[Influence of ouabain on the electrophoretic mobility of erythrocytes in 7 patients with Duchenne's muscular dystrophy].

作者信息

Szibor R, Redmann K, Keike H, Müller K

出版信息

Helv Paediatr Acta. 1976 Oct;31(3):249-56.

PMID:977375
Abstract

Measurements of electrophoretic mobility of erythrocytes under the influence of ouabain were carried out on seven patients suffering from progressive Duchenne's muscular dystrophy. While ouabain-treated erythrocytes of healthy controls showed a significant decrease (alpha = 0.001) in electrophoretic mobility, an increase was found in five of the patients, and two patients revealed a slight drop in electrophoretic mobility. A significant difference (alpha = 0.001) was obtained in comparing the control group of patients. Initial trial measurements suggested that such a difference is also true for some other forms of muscular dystrophy and Werdnig-Hoffmann's spinal muscular atrophy.

摘要

对7例进行性杜氏肌营养不良患者进行了哇巴因影响下红细胞电泳迁移率的测量。健康对照者经哇巴因处理的红细胞电泳迁移率显著降低(α = 0.001),而5例患者的红细胞电泳迁移率升高,2例患者的电泳迁移率略有下降。在比较患者对照组时获得了显著差异(α = 0.001)。初步试验测量表明,这种差异在其他一些形式的肌营养不良和韦尔纳-霍夫曼脊髓性肌萎缩中也存在。

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Helv Paediatr Acta. 1976 Oct;31(3):249-56.
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