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The ubiquitin pathway in Parkinson's disease.

作者信息

Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E, Harta G, Brownstein M J, Jonnalagada S, Chernova T, Dehejia A, Lavedan C, Gasser T, Steinbach P J, Wilkinson K D, Polymeropoulos M H

出版信息

Nature. 1998 Oct 1;395(6701):451-2. doi: 10.1038/26652.

DOI:10.1038/26652
PMID:9774100
Abstract
摘要

相似文献

1
The ubiquitin pathway in Parkinson's disease.帕金森病中的泛素途径。
Nature. 1998 Oct 1;395(6701):451-2. doi: 10.1038/26652.
2
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants.帕金森病相关的人泛素羧基末端水解酶L1变体的结构和水解酶活性改变。
Biochem Biophys Res Commun. 2003 Apr 25;304(1):176-83. doi: 10.1016/s0006-291x(03)00555-2.
3
An Ile93Met substitution in the UCH-L1 gene is not a disease-causing mutation for idiopathic Parkinson's disease.UCH-L1基因中的Ile93Met替换不是特发性帕金森病的致病突变。
Chin Med J (Engl). 2003 Feb;116(2):312-3.
4
Monogenic Parkinsonisms and the genetics of Parkinson's disease.
Funct Neurol. 2001 Jan-Mar;16(1):35-44.
5
Intron-exon structure of ubiquitin c-terminal hydrolase-L1.泛素羧基末端水解酶-L1的内含子-外显子结构
DNA Res. 1998 Dec 31;5(6):397-400. doi: 10.1093/dnares/5.6.397.
6
Etiology of Parkinson's disease: Genetics and environment revisited.帕金森病的病因:重新审视遗传与环境因素
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):13972-4. doi: 10.1073/pnas.242594999. Epub 2002 Oct 21.
7
cDNA cloning and tissue distribution of a rat ubiquitin carboxyl-terminal hydrolase PGP9.5.
J Biochem. 1992 Jul;112(1):28-32. doi: 10.1093/oxfordjournals.jbchem.a123860.
8
Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases.去泛素化酶的底物特异性:泛素C末端水解酶
Biochemistry. 1998 Mar 10;37(10):3358-68. doi: 10.1021/bi972274d.
9
Structural basis for the specificity of ubiquitin C-terminal hydrolases.泛素C末端水解酶特异性的结构基础。
EMBO J. 1999 Jul 15;18(14):3877-87. doi: 10.1093/emboj/18.14.3877.
10
Cloning and analysis of expression of a ubiquitin carboxyl terminal hydrolase expressed during oogenesis in Drosophila melanogaster.
Dev Biol. 1993 May;157(1):214-23. doi: 10.1006/dbio.1993.1125.

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Role of Cellular Senescence in Parkinson's Disease: Potential for Disease-Modification Through Senotherapy.
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Ubiquitin C-Terminal Hydrolase L1 (UCHL1), Beyond Hydrolysis.泛素C末端水解酶L1(UCHL1),超越水解作用。
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Associations among blood biomarkers, clinical subtypes, and prognosis in Parkinson's disease.帕金森病中血液生物标志物、临床亚型和预后之间的关联。
Clin Park Relat Disord. 2025 Mar 11;12:100313. doi: 10.1016/j.prdoa.2025.100313. eCollection 2025.
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The role of ubiquitin C-terminal hydrolase (UCH-L1) and protein S100B in differentiating patients with epileptic and psychogenic non-epileptic seizures - Pilot study.泛素羧基末端水解酶(UCH-L1)和蛋白S100B在鉴别癫痫性发作和精神性非癫痫性发作患者中的作用——初步研究。
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Ubiquitin-Proteasome-Mediated Protein Degradation and Disorders of the Central Nervous System.泛素-蛋白酶体介导的蛋白质降解与中枢神经系统疾病
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Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.USP14 通过调节帕金森病中的 S100A8/A9 来去除α-突触核蛋白。
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