Gelatt K N, Henderson J D, Steffen G R
J Am Vet Med Assoc. 1976 Nov 1;169(9):980-4.
A method was determined for fluorescein angiography of the ocular fundus of the laboratory Beagle, using a portable fluorescein fundus camera. A 10% solution of sodium fluorescein was injected by a syringe pump in the right cephalic vein of each dog. Acepromazine maleate (0.5 mg/kg, IV) with ketamine hydrochloride (10 mg/kg, IM) provided chemical restraint. Of the 10-, 25-, and 50-mg/kg dosages of fluorescein, 25 mg/kg permitted satisfactory fluorescence of the choroidal and retinal vasculature and the recirculation phase. High-speed color film permitted good quality photography of the tapetal and nontapetal retinal vessels. Reduced retinal blood vessel and pigment epithelium permeability was demonstrated by fluorescein angiography in dogs with chorioretinitis associated with systemic blastomycosis, retinitis associated with distemper, serous retinal detachment, and preretinal hemorrhage.
采用便携式荧光素眼底照相机，确定了一种对实验用比格犬眼底进行荧光素血管造影的方法。通过注射泵将10%的荧光素钠溶液注入每只犬的右侧头静脉。马来酸乙酰丙嗪（0.5毫克/千克，静脉注射）与盐酸氯胺酮（10毫克/千克，肌肉注射）联合使用提供化学保定。在荧光素10毫克/千克、25毫克/千克和50毫克/千克的剂量中，25毫克/千克可使脉络膜和视网膜血管以及再循环期产生令人满意的荧光。高速彩色胶片可对毯状和非毯状视网膜血管进行高质量摄影。荧光素血管造影显示，患有与全身性芽生菌病相关的脉络膜视网膜炎、与犬瘟热相关的视网膜炎、浆液性视网膜脱离和视网膜前出血的犬，视网膜血管和色素上皮的通透性降低。
