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寻求治疗的更年期女性:两家大学更年期诊所的比较。

Treatment-seeking women at menopause: a comparison between two university menopause clinics.

作者信息

McKinney K A, Severino M, McFall P, Burry K, Thompson W

机构信息

Department of Obstetrics and Gynaecology, Queen's University Belfast, Northern Ireland.

出版信息

Menopause. 1998 Fall;5(3):174-7.

PMID:9774764
Abstract

OBJECTIVE

We wished to determine the expectations of women about the benefits of hormone replacement therapy (HRT) and how these expectations may be influenced by cultural factors and previous experience of disease by the patient or in their families.

DESIGN

The attitudes of patients seeking HRT in Belfast, United Kingdom (n = 218) and Portland, USA (n = 100) were compared at their first clinic attendance using a questionnaire. Physical and mental health issues, previous use of HRT and continuance on treatment were compared.

RESULTS

Belfast women were less healthy than their Portland counterparts, with a higher prevalence of cardiovascular disease and psychiatric disorders (p < 0.05). Belfast patients showed a significantly lower continuance with treatment (p < 0.01). Collectively, the patients ranked relief of menopausal symptoms as their main expectation from HRT followed by osteoporosis protection, psychiatric relief and cardioprotection. The Belfast group had higher expectations for the relief of psychological/psychiatric problems (p < 0.01). All women with a family history of cardiac disease or fractures were more concerned for the protective effects of HRT than those women with no relevant family history (p < 0.05). There were cultural difference in expectations from HRT with Belfast women expecting more psychological/psychiatric relief and therefore trying a greater number of preparations.

CONCLUSIONS

These findings suggest that menopausal women in both countries are well informed about the potential protective benefits of HRT, and now expect an improvement in the quality of their lives well beyond the relief of menopausal symptoms.

摘要

目的

我们希望确定女性对激素替代疗法(HRT)益处的期望,以及这些期望如何受到文化因素以及患者本人或其家族既往疾病经历的影响。

设计

采用问卷调查法,比较了英国贝尔法斯特(n = 218)和美国波特兰(n = 100)首次就诊寻求HRT治疗的患者的态度。比较了她们的身心健康问题、既往HRT使用情况及持续治疗情况。

结果

贝尔法斯特的女性健康状况不如波特兰的女性,心血管疾病和精神疾病的患病率更高(p < 0.05)。贝尔法斯特的患者治疗持续率显著更低(p < 0.01)。总体而言,患者将缓解更年期症状列为HRT的主要期望,其次是预防骨质疏松症、缓解精神问题和心脏保护作用。贝尔法斯特组对缓解心理/精神问题的期望更高(p < 0.01)。所有有心脏病或骨折家族史的女性比没有相关家族史的女性更关注HRT的保护作用(p < 0.05)。对HRT的期望存在文化差异,贝尔法斯特的女性期望获得更多心理/精神方面的缓解,因此尝试更多的制剂。

结论

这些发现表明,两国的更年期女性都充分了解HRT的潜在保护益处,并且现在期望生活质量得到改善,而不仅仅是缓解更年期症状。

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