Loizzi M, Sardelli P, Sollitto F, Bolognese R, Lopez C, Pizzigallo M A, Lacitignola A
Cattedra di Chirurgia Toracica, Università degli Studi, Bari.
Minerva Chir. 1998 Jun;53(6):489-95.
The purpose of this study is to investigate the value of surgical treatment for lung cancer in the elderly. Results are compared with findings in younger patients operated on during the same period (1985-1990).
137 patients 70 years of age or older (range: 70 yrs-87 yrs) (group A) underwent surgical resection [pneumonectomy in 19 (13.8%), lobectomy or bilobectomy in 84 (61.3%), segmentectomy or wedge resection in 22 (16%)]. In group B (younger patients) 561 were treated by pneumonectomy in 156 (27.8%), lobectomy or bilobectomy in 294 (52.4%) and segmentectomy or wedge resection in 64 (11.4%).
The overall 2-year survival rate was 64.6% in group A and 61.4% in B. The 5-year survival rate was 36.2% (group A) and 43.2% (group B).
These data suggest that advanced age should not be a contraindication to curative pulmonary resections. More attention must be paid to pre-codiseases of the increasing risk of postoperative complications.
本研究旨在探讨老年肺癌患者手术治疗的价值。将结果与同期（1985 - 1990年）接受手术的年轻患者的结果进行比较。
137例70岁及以上患者（年龄范围：70岁 - 87岁）（A组）接受了手术切除[19例（13.8%）全肺切除术，84例（61.3%）肺叶切除术或双肺叶切除术，22例（16%）肺段切除术或楔形切除术]。B组（年轻患者）561例，其中156例（27.8%）接受全肺切除术，294例（52.4%）接受肺叶切除术或双肺叶切除术，64例（11.4%）接受肺段切除术或楔形切除术。
A组2年总生存率为64.6%，B组为61.4%。5年生存率A组为36.2%，B组为43.2%。
这些数据表明，高龄不应成为根治性肺切除术的禁忌证。必须更加关注增加术后并发症风险的基础疾病。
