Caldironi M W, Mazzucco M, Aldinio M T, Paccagnella D, Zani S, Pontini F, De Bellis M E, Rebuffi A G, Costantin G
Divisione Medica III, Azienda Ospedale, Padova.
Minerva Chir. 1998 Jun;53(6):505-9.
Personal experience with fine-needle aspiration biopsy (FNAB) performed in 114 patients (42 males and 72 females) with hepatic angiomas, in whom imaging techniques did not allow a definite diagnosis, is reported. FNAB was made on 57.9% of the cases for atypical US pattern of the nodule, on 52.6% for a previous cancer history, with both conditions on 10.5%. The procedure was carried out by cyto-assistance for collecting material and a rapid stain diagnosis with an average of 2 biopsies per patient. Diagnostic accuracy was evaluated with following laparoscopy in 25 cases; surgery in 4 cases; angiography in 6 cases and US follow-up for 1 year at least in 78 cases (1 drop-out).
One false-negative and 4 false-positives were detected with an overall accuracy of 96%. Two minor accidents were observed, due to a profuse bleeding of giant angiomas and resolved with medical care.
Therefore, in case of angiomas larger than 5 cm, the use of laparoscopy after FNAB to control the bleeding and to confirm the diagnosis is suggested.
报告了对114例肝血管瘤患者(42例男性和72例女性)进行细针穿刺活检(FNAB)的个人经验,这些患者的影像学检查无法做出明确诊断。57.9%的病例因结节的非典型超声表现进行FNAB,52.6%因既往有癌症病史进行FNAB,10.5%的病例两种情况都有。该操作通过细胞辅助收集材料,并进行快速染色诊断,平均每位患者进行2次活检。通过对25例患者进行后续腹腔镜检查、4例患者进行手术、6例患者进行血管造影以及至少78例患者(1例失访)进行1年的超声随访来评估诊断准确性。
检测到1例假阴性和4例假阳性,总体准确率为96%。观察到2例轻微并发症,原因是巨大血管瘤大量出血,经医疗处理后得到解决。
因此,对于直径大于5cm的血管瘤,建议在FNAB后使用腹腔镜检查以控制出血并确认诊断。