Chen Fei, Wang Bin, Chen Lu-zeng
Department of Diagnostic Ultrasound, Peking University First Hospital, Beijing 100034, China.
Zhonghua Yi Xue Za Zhi. 2007 Mar 27;87(12):823-5.
To compare safety and sensitivity in diagnosis of liver lesion between ultrasound-guided 16 gauges (G) and 18 G core needle biopsy.
Ultrasound-guided 16 G needle biopsy was performed in 141 patients, 77 males and 64e females, aged 51.2, and ultrasound-guided 18 G needle biopsy was performed in 105 patients, 54 males and 51 females, aged 60.1. The final diagnosis was based on the post-operative pathological examination and/or the results of 6-month follow-up.
In the In the ultrasound-guided 16 G needle biopsy, 171 passes were performed with an average of 1.21 pass, a sensitivity rate of 95.9%, and a specificity rate of 100%, and abdominal pain occurred in 51 cases, and bleeding occurred in 3 cases. In the ultrasound-guided 18 G needle biopsy, 161 passes were performed with an average of 1.53 passes, a sensitivity rate of 83.8%, and a specificity rate of 100%, and abdominal pain occurred in 37 cases, and bleeding occurred in 2 cases. The number of pass of the 16 G was significantly less then that of the 128 G group (P = 0.000). The sensitivity rate of the 16 G needle biopsy was significantly higher than that of the 18 G group (P = 0.46).
Ultrasound-guided 16 gauges core needle biopsy is safe for the diagnosis of hepatic disease and more sensitive than the 18 G biopsy.
比较超声引导下16号（G）与18G粗针活检诊断肝脏病变的安全性和敏感性。
对141例患者进行超声引导下16G针活检，其中男性77例，女性64例，年龄51.2岁；对105例患者进行超声引导下18G针活检，其中男性54例，女性51例，年龄60.1岁。最终诊断基于术后病理检查和/或6个月随访结果。
在超声引导下16G针活检中，进针171次，平均1.21次，敏感率95.9%，特异率100%，51例出现腹痛，3例发生出血。在超声引导下18G针活检中，进针161次，平均1.53次，敏感率83.8%，特异率100%，37例出现腹痛，2例发生出血。16G组进针次数显著少于18G组（P = 0.000）。16G针活检的敏感率显著高于18G组（P = 0.46）。
超声引导下16G粗针活检对肝脏疾病的诊断安全，且比18G活检更敏感。
