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[台湾北部两种白纹伊蚊品系对日本脑炎病毒易感性的研究]

[Studies on the susceptibility of two northern Taiwan strains of Aedes albopictus mosquitoes to Japanese encephalitis virus].

作者信息

Weng M H, Lien J C, Show Y S

机构信息

Epidemiology Section, Institute of Preventive Medicine, National Defence Medical Center, Sanhsia.

出版信息

Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1995 Feb;28(1):39-46.

PMID:9774983
Abstract

Aedes albopictus is a dominant mosquito species in northern Taiwan. In laboratory, the vector competence of 2 geographical strains of Aedes albopictus mosquitoes to NT 113 strain of Japanese encephalitis virus was examined. The mosquito infection dose50 (MI-D50) of Sanhsia (SH) strain by intrathoracic (i.t.) inoculation was shown to be -1.1 log WMICLD50 (weanling mice intracerebrum lethal dose), while that of Yungho (YH) strain was -2.0 log WMICLD50. The infection dose for 50% mosquitoes transmission (MTID50) by i.t. inoculation was 3.5 log with SH strain but no transmission occurred with YH strain. By feeding sweetened blood-virus mixture, the MID50 with SH strain was 2.7 log though YH strain did not attain 50% infection rate. By viremic mouse blood feeding, the highest infection rate for both strains was about 30%. No evidence of virus transmission was demonstrated by oral infection.

摘要

白纹伊蚊是台湾北部的优势蚊种。在实验室中,检测了2个地理株白纹伊蚊对日本脑炎病毒NT 113株的媒介能力。经胸腔接种,三峡(SH)株白纹伊蚊的半数感染剂量(MI-D50)为-1.1 log WMICLD50(断奶小鼠脑内致死剂量),而永和(YH)株为-2.0 log WMICLD50。经胸腔接种,50%蚊虫传播的感染剂量(MTID50),SH株为3.5 log,而YH株未发生传播。通过喂食加糖的病毒血液混合物,SH株的MID50为2.7 log,而YH株未达到50%的感染率。通过喂食病毒血症小鼠血液,两株的最高感染率约为30%。经口感染未显示病毒传播的证据。

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