Wong Y M, Clark J B, Faris I B, Styles C B, Kiss J A
Melbourne University, Department of Surgery, Geelong Hospital, Victoria, Australia.
Eye (Lond). 1998;12 ( Pt 3a):367-73. doi: 10.1038/eye.1998.88.
To determine the profile of blood flow velocities and resistive indices in the ocular vessels of patients with atherosclerotic carotid disease and characterise the effect of endarterectomy on these parameters.
Following a preliminary study on healthy volunteers, ophthalmic colour Doppler ultrasound examinations were performed on 27 male and 11 female patients with carotid disease. These measurements were compared with central retinal artery perfusion pressures and intraoperative internal carotid artery stump pressures.
Significant changes were seen on the endarterectomised side. The peak systolic velocity in the ophthalmic artery, and resistive indices in the ophthalmic artery, central retinal artery and nasal posterior ciliary artery, rose from pre-operative values. No correlation between colour Doppler ultrasound measurements and intraoperative internal carotid artery stump pressures was present. When compared with ophthalmodynamometry readings, a relationship was noted with maximum velocities in the central retinal vein.
Carotid endarterectomy alters the haemodynamics in selected vessels of the ocular circulation as measured by colour Doppler ultrasound, but more work is required to determine the clinical utility of this investigative modality.
确定动脉粥样硬化性颈动脉疾病患者眼部血管的血流速度和阻力指数特征，并描述动脉内膜切除术对这些参数的影响。
在对健康志愿者进行初步研究之后，对27例男性和11例女性颈动脉疾病患者进行了眼科彩色多普勒超声检查。将这些测量结果与视网膜中央动脉灌注压和术中颈内动脉残端压力进行比较。
在内膜切除侧观察到显著变化。眼动脉的收缩期峰值速度以及眼动脉、视网膜中央动脉和鼻后睫状动脉的阻力指数均高于术前值。彩色多普勒超声测量结果与术中颈内动脉残端压力之间无相关性。与眼血流动力学测量读数相比，发现与视网膜中央静脉的最大速度存在关联。
颈动脉内膜切除术可改变彩色多普勒超声测量的眼部循环中特定血管的血流动力学，但需要更多研究来确定这种检查方式的临床实用性。
