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一项关于10/0可吸收聚乙醇酸缝线用于角膜切口超声乳化术的前瞻性对照研究。

A prospective controlled study of a 10/0 absorbable polyglactin suture for corneal incision phacoemulsification.

作者信息

Bainbridge J W, Teimory M, Kirwan J F, Rostron C K

机构信息

Department of Ophthalmology, St George's Hospital, London, UK.

出版信息

Eye (Lond). 1998;12 ( Pt 3a):399-402. doi: 10.1038/eye.1998.94.

Abstract

PURPOSE

To evaluate the performance of a 10/0 monofilament absorbable polyglactin suture for temporal 5.2 mm corneal incision phacoemulsification.

METHODS

A prospective randomised controlled study of 49 patients undergoing phacoemulsification with a sutured temporal 5.2 mm corneal section was conducted to compare the refractive results and complications of a 10/0 monofilament absorbable polyglactin suture with 10/0 nylon.

RESULTS

Thirty-eight patients completed the study. There was no significant difference in induced astigmatism between the two groups. All absorbable sutures were intact at 1 week. Six weeks post-operatively the absorbable suture was still intact in 1 (6%) patient, present but broken in 4 (24%) and completely absent in 12 (70%) patients. All polyglactin sutures had been completely absorbed by 12 weeks. Absorption of the polyglactin sutures was associated with mild localised corneal haze in 3(18%) cases (p = 0.055). One of the 18 patients (6%) in the polyglactin suture group presented with iris prolapse associated with knot failure 1 week post-operatively. There was no significant difference in foreign body symptoms between the two groups.

CONCLUSIONS

10/0 polyglactin sutures maintain adequate tensile strength during the immediate post-operative period for small incision surgery and are associated with minimal induction of astigmatism. Their subsequent absorption obviates the need for routine suture removal. Suture absorption is well tolerated although in some cases a mild degree of local tissue reaction raises concern about possible mechanisms of absorption. The risk of knot failure may be reduced by an alternative suture tying technique. 10/0 monofilament polyglactin is an attractive option when a suture is required during small incision cataract surgery.

摘要

目的

评估10/0单丝可吸收聚乙醇酸缝线用于颞侧5.2mm角膜切口白内障超声乳化手术的效果。

方法

对49例行颞侧5.2mm角膜切口白内障超声乳化手术并使用缝线的患者进行前瞻性随机对照研究,比较10/0单丝可吸收聚乙醇酸缝线与10/0尼龙缝线的屈光结果及并发症。

结果

38例患者完成研究。两组之间诱导散光无显著差异。所有可吸收缝线在1周时均完整。术后6周,1例(6%)患者的可吸收缝线仍完整,4例(24%)存在但已断裂,12例(70%)患者的缝线完全消失。所有聚乙醇酸缝线在12周时已完全吸收。聚乙醇酸缝线吸收与3例(18%)患者出现轻度局限性角膜混浊相关(p = 0.055)。聚乙醇酸缝线组18例患者中有1例(6%)在术后1周出现与线结失败相关的虹膜脱垂。两组之间异物感症状无显著差异。

结论

10/0聚乙醇酸缝线在小切口手术后的即刻术后期间维持足够的拉伸强度,且诱导散光最小。其随后的吸收消除了常规拆线的必要性。缝线吸收耐受性良好,尽管在某些情况下轻度局部组织反应引发了对可能吸收机制的关注。采用替代的缝线打结技术可能会降低线结失败的风险。在小切口白内障手术需要缝线时,10/0单丝聚乙醇酸是一个有吸引力的选择。

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