婴幼儿期和儿童期生殖细胞肿瘤：一所机构的经验与其他研究对比

Germ cell tumor in infancy and childhood: experience at one institute compared to other studies.

作者信息

Hsieh Y L, Hwang B, Wei C F, Ng H T

机构信息

Department of Pediatrics, Veterans General Hospital-Taipei, Taiwan, R.O.C.

出版信息

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1998 Jul-Aug;39(4):253-6.

PMID:9775496

Abstract

To understand the difference in incidence and distribution of germ cell tumor (GCT) between cases seen in this institute and Western studies, 98 cases of GCTs collected from 1979 to 1996 were included 50 with gonadal GCTs, 9 with mediastinal GCTs; 9 with retroperitoneal GCTs, 10 with sacrococcygeal GCTs and 20 with intracranial GCTs; all were analyzed retrospectively by chart review. The incidences of testicular and intracranial GCT in all GCTs were higher in this study, i.e. 26.5%(26/98) and 20.4%(20/98) compared to 7% and 6% of American reports. But the incidence of sacrococcygeal GCT in all GCTs was lower in this study, i.e. 10.2%(10/98) compared to 41% of American reports. The incidences of testicular and ovarian GCT in all GCTs were about the same in this study, i.e. 26.5%(26/98) and 24.5%(24/98) compared to 7% and 29% of American reports; 51%(50/98) of all GCTs were gonadal in this study compared to 36% in the American reports.

摘要

为了解本机构所见病例与西方研究中生殖细胞肿瘤（GCT）的发病率及分布差异，纳入了1979年至1996年收集的98例GCT病例，其中50例为性腺GCT，9例为纵隔GCT，9例为腹膜后GCT，10例为骶尾部GCT，20例为颅内GCT；所有病例均通过查阅病历进行回顾性分析。本研究中，所有GCT病例中睾丸和颅内GCT的发病率较高，分别为26.5%（26/98）和20.4%（20/98），而美国报告中的发病率分别为7%和6%。但本研究中所有GCT病例中骶尾部GCT的发病率较低，为10.2%（10/98），而美国报告中的发病率为41%。本研究中所有GCT病例中睾丸和卵巢GCT的发病率大致相同，分别为26.5%（26/98）和24.5%（24/98），而美国报告中的发病率分别为7%和29%；本研究中所有GCT病例的51%（50/98）为性腺GCT，而美国报告中的比例为36%。