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美沙酮维持疗法对海洛因成瘾的有效性。

Effectiveness of methadone maintenance for heroin addiction.

作者信息

Murray J B

机构信息

Psychology Department, St. John's University, Jamaica, NY 11439, USA.

出版信息

Psychol Rep. 1998 Aug;83(1):295-302. doi: 10.2466/pr0.1998.83.1.295.

Abstract

Methadone maintenance programs have effectively reduced heroin dependency and are available in most countries affected by heroin addiction. Methadone, developed in Germany during World War II as a pain killer, does not have the euphoric effects of heroin and the goal of treatment is to substitute methadone for heroin use. Recidivism is probably a life-long risk. Methadone maintenance programs began in the 1960s in the United States in New York City. Once tolerance is developed, it may be used continually without harmful side effects. Dosage is important for effectiveness as are counseling, rehabilitation services, and employment support. Reduction in criminality and AIDS has been associated with methadone maintenance programs.

摘要

美沙酮维持治疗项目已有效降低了海洛因依赖,并且在大多数受海洛因成瘾影响的国家都可提供。美沙酮于第二次世界大战期间在德国作为一种止痛药研制而成,它没有海洛因带来的欣快感,治疗目标是用美沙酮替代海洛因使用。复吸可能是一种终身风险。美沙酮维持治疗项目于20世纪60年代在美国纽约市启动。一旦产生耐受性,它可以持续使用而无有害副作用。剂量对于疗效很重要,咨询、康复服务和就业支持也同样重要。美沙酮维持治疗项目与犯罪率降低及艾滋病减少有关。

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